The Global Leader in Preclinical Ophthalmic Research

EyeCRO provides a fully integrated platform for preclinical ophthalmic drug development, from in-life efficacy studies through bioanalytical analysis, all under one roof. With over two decades of experience in vision research, our expert scientists can help you select the right model and experimental design to achieve your research and development goals. We also offer Toxicology/PK studies and eyedrop formulations in MiDROPS®.
Contact Us Our Models Bioanalytical Services

One Partner. Complete Data.

Most preclinical ophthalmic programs require sponsors to coordinate between separate CROs for in-life studies and bioanalytical work, adding cost, complexity, and delays from sample shipping and cross-site communication. EyeCRO eliminates that friction.

Our dedicated bioanalytical laboratory operates alongside our in-life research teams, providing LC-MS/MS, HPLC, ELISA, and additional capabilities with optimized ocular tissue extraction protocols for mouse, rat, and rabbit. Studies move from dosing to quantification without delays, sample degradation risks, or coordination across vendors.

One study plan. One point of contact. One complete dataset—delivered faster

Microemulsion Drug Ocular Penetration System

MiDROPS®

MiDROPS® was developed to allow for eyedrop formulations of small molecules that are lipophilic. This technology represents a fundamentally new approach for ophthalmic drug delivery using microemulsions which are thermodynamically stable. These self-assembling vehicles can formulate high concentrations of drugs and deliver them in abundant quantities to both the anterior segment and posterior segment.  Our broad patents are issued in the US and Worldwide and protect millions of different formulations covered in our library.

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Capabilities

From study design to final report, EyeCRO provides end-to-end preclinical research services with best-in-class ophthalmic expertise.

Dosing & Drug Delivery

Intravitreal, subretinal, subconjunctival, topical, and systemic routes of administration across mouse, rat, and rabbit.

Ophthalmic Imaging & Physiology

In vivo retinal imaging including ERG, OCT, fundus photography, and slit-lamp biomicroscopy across multiple species.

Histology & Pathology

Full histological processing, H&E staining, IHC, and digital image quantification for ocular tissue analysis.

Bioanalytical Services

LC-MS/MS, automated sample preparation, multiplex immunoassay, and protein quantification from ocular tissues and fluids.

Proprietary Software & Analysis

Custom-built analysis pipelines for fluorophotometry, retinal imaging quantification, and automated data processing.

News & Events

  • One CRO. Complete Dataset.

    ByConnor Hodde

    When a preclinical efficacy study wraps up at EyeCRO, ocular tissues move directly from our animal facility to our bioanalytical lab. No third-party handoffs. No waiting in an external lab’s queue. Sponsors receive a single integrated dataset covering both in-life endpoints and bioanalytical quantitation from the team that ran the entire study. LC-MS/MS Quantitation Our…

  • EyeCRO at ARVO 2026

    ByConnor Hodde

    EyeCRO will be attending the 2026 ARVO Annual Meeting in Denver, Colorado, May 3-7. ARVO brings together over 11,000 eye and vision researchers from 75 countries, and it remains the most important meeting in our field for sharing new findings and building collaborations. This year’s theme focuses on how innovative vision research is driving the…

  • EyeCRO Contributes to Evaluation of SPVN06 Gene Therapy

    ByConnor Hodde

    A new Gene Therapy publication details the safety and biodistribution assessment of SPVN06, a mutation-independent gene therapy in development for rod–cone dystrophies (RCDs). These inherited retinal disorders are a leading cause of vision loss and can result from mutations in more than 100 different genes, which makes developing broadly applicable treatments challenging. SPVN06 is an…

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